What are bacteriophages

What are bacteriophages or phages?

The bacteriophages were discovered in 1917 by the French microbiologist Felix d'Herelle. Through his research he recognized the effect against pathogenic bacteria and suggested using these bacteriophages for the prevention and treatment of infectious diseases.

In the 1930s, many laboratories and pharmaceutical companies began developing and manufacturing bacteriophages for medical use.
However, the discovery of the antibiotic in the 1930s lost interest in bacteriophages, as antibiotics kill all microbes and antibiotics were easier to make than the bacteriophage products. Therefore phage therapy is forgotten.

Only a few scientific centers in Eastern Europe continued their work with the bacterial viruses.
With the emergence of multi-residue germs, the interest in bacteriophages has increased again.

Which infections could bacteriophages treat?

Bacteriophages are used in adults and children in Eastern Europe to prevent and treat the following diseases:

• bacterial infectious diseases of the gastrointestinal tract (enterocolitis, gastroenterocolitis, salmonellosis, shigellosis, dysbacteriosis, etc.);
• bacterial diseases of the ears, oral cavity, throat, bronchi and lungs (otitis, stomatitis, periodontitis, sinusitis, pharyngitis, laryngitis, angina, tracheitis, bronchitis, pleurisy, pneumonia, etc.);
• bacterial eye disease (conjunctivitis, keratoconjunctivitis, etc.);
• surgical infections (treatment of surgical and infected wounds, abscesses, phlegmon, boils, carbuncles, etc.)
• Ligament wounds
• Genitourinary infections (cystitis, urethritis, colpitis, pyelonephritis, etc.).

Bacteriophages are used both independently and in combination with other antibacterial agents.
Phage therapy is particularly useful if the pathogen bacterium is resistant to antibiotics and if the patient is intolerant to antibiotics.
In Eastern Europe, bacteriophages are administered in liquid form. The bacteriophages are applied to the infected areas by application, rinsing or inlets.